After only playing in four games last season, McCaffrey is aiming to make a massive comeback to help get the Niners back in ...

A revitalized Christian McCaffrey took the ball on the 49ers’ opening play and was off and running in a heavy workload ...

Also, rookie tackle Connor Colby impressed while QB Brock Purdy was sharper than he was in last week’s joint practice against ...

HENDERSON, Nev. — Outside of a few brief skirmishes, the Las Vegas Raiders and San Francisco 49ers were on good behavior ...

San Francisco 49ers head coach Kyle Shanahan says Brandon Aiyuk will be ready around the one third mark of the season.

The 49ers opened their preseason with a 30-9 loss against the Denver Broncos from Levi's Stadium in Santa Clara, Calif. While ...

Kyle Shanahan shared his thoughts on the Denver Broncos' ascending second-year quarterback after Thursday's joint practice.

San Francisco 49ers wide receiver Brandon Aiyuk hasn't played since Oct. 20 because of a significant knee injury that limited ...

No starters on the San Francisco 49ers, except for left guard Ben Bartch, played in the first preseason game against the Denver Broncos. The 49ers don't usually ...

Most of the San Francisco 49ers' starters watched from the sidelines during last weekend's preseason opener against the ...

Head coach Kyle Shanahan said Thursday that Bosa is dealing with neck soreness and could be back at practice next week, Nick Wagoner of ESPN.com reports.

All signs point to Aiyuk starting the season on the reserve/PUP list, which would sideline him for the first four weeks of ...