With the AL East leaders expected to start three left-handed starters in the series at Fenway Park, Alex Cora will turn to Rob Refsnyder and Romy González in his lineup.

Check, Marcelo Mayer. Check. Roman Anthony. Check. The Red Sox and the Big Three have done what looked almost impossible to do: they’ve stopped the bleeding.

Mayer, who hits seventh for the Red Sox, gave Boston the lead in the second inning Wednesday. With the game tied 1-1, Mayer launched a first-pitch slider from Rays starter Zack Littell over the right-field wall at Fenway Park.