LOUISVILLE, Ky. (WDRB) -- Interstate 65 near Hospital Curve in downtown Louisville is open again following a weekend closure. The left and center lanes on I-65 North and the left lane on I-65 South ...

In a notification sent at 6:57 p.m. Tuesday, INDOT reported that all lanes of I-65 southbound had reopened at mile marker 218 ...

A 19-year-old Lester man was arrested Saturday night after police say he led officers on a high-speed chase down Interstate 65, weaving through traffic and nearly causing crashes before spike strips ...

A hit-and-run on Thursday, July 31st killed 33-year-old Devin Chapman Sr., on Interstate-65. So far, no arrests have been made. His family is now pleading for s ...

A man is dead after a multiple big-rig collision late Monday night that will have southbound lanes of Interstate 65 closed in ...

A truck driver died in a fatal crash involving three semis Monday night on Interstate 65 in northwest Indiana.

RENSSELAER, Ind. (WLFI) — A truck driver died in a multi-vehicle crash on Interstate 65 on Monday night. The crash occurred ...

Indiana State Police say reckless driving by semi-trailer trucks resulted in a fatal crash Monday night that left the ...

A section of Interstate 65 in Louisville will be closed for more than a month, officials said. Southbound lanes of the highway closed Tuesday night at the John F. Kennedy Memorial Bridge and will ...

A single-vehicle crash on Interstate 65 has led to a complete road closure near mile marker 306. The incident occurred at ...

Police believe Daryus Chambers, 37, crashed into a tractor-trailer and then was run over by another motorcyclist.

Hoosiers love to complain about our roads, but no one wants to pay to improve them. Tolling is where the money is at. And it's a lot of money.